Human natural killer cell activity is augmented by interferon via recruitment of 'pre-NK' cells.

@article{Saksela1979HumanNK,
  title={Human natural killer cell activity is augmented by interferon via recruitment of 'pre-NK' cells.},
  author={Eero Saksela and Tuomo Timonen and Kari Cantell},
  journal={Scandinavian journal of immunology},
  year={1979},
  volume={10 3},
  pages={257-66}
}
Contact with various cell-line targets increases the natural killer (NK) activity of human lymphocytes. Supernatants of such 20 h co-cultures augment the NK activity of virgin lymphocyte populations, and the augmenting factor penetrates 0.2 micrometer Millipore filters. The supernatants also contain interferon, and partially purified human leucocyte interferon increases NK activity when added to 20 h assays with 51Cr-labelled K-562 target cells. Potent anti-interferon antiserum added to the co… CONTINUE READING

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