Human natural anti-alpha-galactosyl IgG. II. The specific recognition of alpha (1----3)-linked galactose residues

@article{Galili1985HumanNA,
  title={Human natural anti-alpha-galactosyl IgG. II. The specific recognition of alpha (1----3)-linked galactose residues},
  author={Uri Galili and Bruce Macher and James A Buehler and Stephen B. Shohet},
  journal={The Journal of Experimental Medicine},
  year={1985},
  volume={162},
  pages={573 - 582}
}
A natural IgG antibody (anti-Gal) with alpha-galactosyl binding specificity has been found in large amounts (0.5 - 1.0% of serum IgG) in all individuals tested. It has been purified by affinity chromatography on a column of melibiose-Sepharose. In addition to its affinity for normal and pathological senescent human red cells, the antibody readily interacts with rabbit red blood cell (RRBC) glycolipids with alpha-galactosyl terminal residues. Two types (glycosidic linkages of 1----3 vs. 1----4… CONTINUE READING
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The natural anti-c~-galactosyl IgG on red cells in sickle cell disease

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Purification and structural elucidation of three different blood-groupB- and I- or i-active glycosphingolipids from rabbit erythrocyte membranes

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