Human muscle sympathetic nerve responses to urocortin-2 in health and stable heart failure.

@article{Chan2015HumanMS,
  title={Human muscle sympathetic nerve responses to urocortin-2 in health and stable heart failure.},
  author={W Y Wandy Chan and Christopher John Charles and C M Frampton and Arthur Mark Richards and Ian George Crozier and Richard W. Troughton and David Lewis Jardine},
  journal={Clinical and experimental pharmacology & physiology},
  year={2015},
  volume={42 9},
  pages={
          888-895
        }
}
Sympatholytic and vasodilator drugs have been of major therapeutic benefit in patients with heart failure (HF). Urocortin-2 (Ucn2) is a small corticotrophin-related peptide distributed throughout the cardiovascular system which inhibits cardiac sympathetic nerve activity (CSNA) and is also a powerful vasodilator. This study analysed the effects of a 60-min… CONTINUE READING