Human mtDNA sublimons resemble rearranged mitochondrial genoms found in pathological states.

@article{Kajander2000HumanMS,
  title={Human mtDNA sublimons resemble rearranged mitochondrial genoms found in pathological states.},
  author={Olli A Kajander and Anja T. Rovio and Kari Majamaa and Joanna Poulton and Johannes N. Spelbrink and Ian J. Holt and Pekka J. Karhunen and Howard T. Jacobs},
  journal={Human molecular genetics},
  year={2000},
  volume={9 19},
  pages={
          2821-35
        }
}
Sublimons, originally identified in plant mitochondria, are defined as rearranged mtDNA molecules present at very low levels. We have analysed the primary structures of sublimons found in human cells and tissues and estimated their abundance. Each tissue of a given individual contains a wide range of different sublimons and the most abundant species differ between tissues in a substantially systematic manner. Sublimons are undetectable in rho(0) cells, indicating that they are bona fide… CONTINUE READING

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