Human monoclonal antibodies directed against toxins A and B prevent Clostridium difficile-induced mortality in hamsters.

@article{Babcock2006HumanMA,
  title={Human monoclonal antibodies directed against toxins A and B prevent Clostridium difficile-induced mortality in hamsters.},
  author={Gregory J. Babcock and Teresa J. Broering and H{\'e}ctor J. Hern{\'a}ndez and Robert B. Mandell and Katherine Donahue and Naomi K Boatright and Anne M Stack and Israel Lowy and Robert Graziano and Deborah C. Molrine and Donna M. Ambrosino and William D Thomas},
  journal={Infection and immunity},
  year={2006},
  volume={74 11},
  pages={6339-47}
}
Clostridium difficile is the leading cause of nosocomial antibiotic-associated diarrhea, and recent outbreaks of strains with increased virulence underscore the importance of identifying novel approaches to treat and prevent relapse of Clostridium difficile-associated diarrhea (CDAD). CDAD pathology is induced by two exotoxins, toxin A and toxin B, which… CONTINUE READING