Human monoclonal antibodies

@article{Cole2004HumanMA,
  title={Human monoclonal antibodies},
  author={Susan P. C. Cole and Barbara G Campling and Tsehay Atlaw and Danuta Kozbor and John C. Roder},
  journal={Molecular and Cellular Biochemistry},
  year={2004},
  volume={62},
  pages={109-120}
}
SummaryThe technology for the production of murine monoclonal antibodies has been refined enormously since its introduction in 1975. However, the technology for generating human monoclonal antibodies has only recently come into its own. In this review, three currently available approaches to the production of human monoclonal antibodies are described. These include the hybridoma technique, based on the fusion of antibody-producing human B lymphocytes with either mouse or human myeloma or… Expand
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