Human mitochondrial thymidine kinase is coded for by a gene on chromosome 16 of the nucleus.

@article{Willecke1977HumanMT,
  title={Human mitochondrial thymidine kinase is coded for by a gene on chromosome 16 of the nucleus.},
  author={Klaus Willecke and T Teber and Raju Suryanarayana Kucherlapati and Frank H. Ruddle},
  journal={Somatic cell genetics},
  year={1977},
  volume={3 3},
  pages={
          237-45
        }
}
The expression of human mitochondrial thymidine kinase (mt TK) was investigated by polyacrylamide electrophoresis in 19 independent human-mouse somatic cell hybrids which allowed all human chromosomes to be analyzed. In 8 hybrid clones the presence of this enzymatic activity could be demonstrated. Human mt TK segregated concordantly with human adenine phosphoribosyltransferase (APRT) and human chromosome 16. Discordant segregation with all other human chromosomes was demonstrated by karyotype… CONTINUE READING
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