Human microbiome, infections, and rheumatic disease

  title={Human microbiome, infections, and rheumatic disease},
  author={Ana Clara Caminer and Rebecca H Haberman and Jose U. Scher},
  journal={Clinical Rheumatology},
Microbes have coevolved with their human hosts for millions of years and are vital to their normal development and homoeostasis. It is now clear that there is direct and indirect cross talk between the microbiome and host immune responses. However, the exact mechanisms for this microbial influence in disease pathogenesis remain elusive and are now a major research focus. 

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