Human microRNA (miR29b) expression controls the amount of branched chain alpha-ketoacid dehydrogenase complex in a cell.

@article{Mersey2005HumanM,
  title={Human microRNA (miR29b) expression controls the amount of branched chain alpha-ketoacid dehydrogenase complex in a cell.},
  author={Benjamin D. Mersey and Peng Jin and Dean J. Danner},
  journal={Human molecular genetics},
  year={2005},
  volume={14 22},
  pages={3371-7}
}
Branched chain amino acids (BCAAs) play critical roles in cell and tissue functions in addition to being important components of protein structure. The multifunctional roles speak to the need for maintaining tight control of their concentration within cells. As the BCAA cannot be made de novo in mammals, their cellular concentration is a function of dietary intake, endogenous protein turnover and catabolism of the three amino acids. The branched chain alpha-ketoacid dehydrogenase (BCKD) complex… CONTINUE READING

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