Human miRNome profiling identifies microRNAs differentially present in the urine after kidney injury.

@article{Ramachandran2013HumanMP,
  title={Human miRNome profiling identifies microRNAs differentially present in the urine after kidney injury.},
  author={Krithika Ramachandran and Janani Saikumar and Vanesa Bijol and Jay L. Koyner and Jing Qian and Rebecca A. Betensky and S. S. Waikar and Vishal S. Vaidya},
  journal={Clinical chemistry},
  year={2013},
  volume={59 12},
  pages={1742-52}
}
BACKGROUND Extracellular microRNAs (miRNAs) have been proposed as potentially robust and stable biomarkers of various disease conditions. The primary objective of this study was to identify miRNAs differentially occurring in the urine that could serve as potential biomarkers of acute kidney injury (AKI), because traditional AKI markers have limitations with respect to sensitivity, specificity, and timeliness of diagnosis. METHODS We profiled 1809 miRNAs in pooled urine samples from 6 patients… CONTINUE READING
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Differentially expressed miRNAs in the plasma may Urinary miRNAs in

  • S Ali, K Almhanna, W Chen, PA Philip, FH Sarkar
  • Kidney Injury Clinical Chemistry
  • 2013

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