Human metapneumovirus bronchiolitis in infancy is an important risk factor for asthma at age 5

  title={Human metapneumovirus bronchiolitis in infancy is an important risk factor for asthma at age 5},
  author={Mar{\'i}a Luz Garc{\'i}a-Garc{\'i}a and Cristina Calvo and Inmaculada Casas and Teresa Bracamonte and Alfonso Pelegr{\'i}n Rell{\'a}n and F. Gozalo and Tbs Ten{\'o}rio and Pilar Pérez-Breña},
  journal={Pediatric Pulmonology},
Human metapneumovirus (hMPV) infection plays an important role in the pediatric respiratory infections. However, little is known about the relationship between hMPV‐bronchiolitis and the development of subsequent wheezing. The aim of this study was to evaluate the outcome at third to fifth year after admission for hMPV‐bronchiolitis and to compare it with children admitted for respiratory syncytial virus (RSV)‐bronchiolitis and with children without lower respiratory disease in the first 2… 
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This review will focus on the epidemiology, transmission, and clinical manifestations in humans as well as the animal models of HMPV pathogenesis and host immune response.


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