Human metabolism of α-pinene and metabolite kinetics after oral administration

@article{Schmidt2015HumanMO,
  title={Human metabolism of α-pinene and metabolite kinetics after oral administration},
  author={Lukas Schmidt and Thomas G{\"o}en},
  journal={Archives of Toxicology},
  year={2015},
  volume={91},
  pages={677-687}
}
We studied the human in vivo metabolism and the elimination kinetics of α-pinene (αPN), a natural monoterpene which commonly occurs in the environment. Four volunteers were exposed to a single oral dose of 10 mg αPN. Each subject provided one pre-exposure and subsequently all post-exposure urine samples up to 24 h after administration. Additionally, blood samples were drawn hourly from two volunteers for 5 h. The analysis of the parent compound in blood was performed by a headspace GC–MS… CONTINUE READING
BETA

Citations

Publications citing this paper.

R-Limonene metabolism in humans and metabolite kinetics after oral administration

  • Archives of Toxicology
  • 2016
VIEW 7 EXCERPTS
CITES BACKGROUND, METHODS & RESULTS
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 31 REFERENCES

Identification of cis- and trans-verbenol in human urine after occupational exposure to terpenes

  • International archives of occupational and environmental health
  • 1990
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Exposure to dust, resin acids, and monoterpenes in softwood lumber mills.

  • AIHAJ : a journal for the science of occupational and environmental health and safety
  • 2000
VIEW 1 EXCERPT
HIGHLY INFLUENTIAL

Sensitive monitoring

B matogr
  • 2013

Emission rates

DX Ho, KH Kim, JR Sohn, YH Oh, JW Ahn
  • 2011
VIEW 1 EXCERPT

The FEMA GRAS

TB Adams, CL Gavin, MM McGowen
  • 2011
VIEW 1 EXCERPT

The FEMA GRAS assessment of aliphatic and aromatic terpene hydrocarbons used as flavor ingredients.

  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 2011
VIEW 1 EXCERPT

Similar Papers

Loading similar papers…