Human mesenchymal stromal cell-derived extracellular vesicles alleviate renal ischemic reperfusion injury and enhance angiogenesis in rats.

@article{Zou2016HumanMS,
  title={Human mesenchymal stromal cell-derived extracellular vesicles alleviate renal ischemic reperfusion injury and enhance angiogenesis in rats.},
  author={Xiangyu Zou and Di Gu and Xiaoyu Xing and Zhongliang Cheng and Dongliang Gong and Guangyuan Zhang and Yingjian Zhu},
  journal={American journal of translational research},
  year={2016},
  volume={8 10},
  pages={4289-4299}
}
BACKGROUND Mesenchymal stromal cells (MSCs) derived extracellular vesicles (EVs) were regarded as a potent medium for kidney injury repair and angiogenesis were regarded as an important step in tissue regeneration. However, the pro-angiogenesis effect of MSC-EVs in ischemia-reperfusion induced kidney injury and its potential mechanisms have yet to be… CONTINUE READING