Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion.

Abstract

Hepatic transdifferentiation of bone marrow cells has been previously demonstrated by intravenous administration of donor cells, which may recirculate to the liver after undergoing proliferation and differentiation in the recipient's bone marrow. In the present study, to elucidate which cellular components of human bone marrow more potently differentiate… (More)

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@article{Sato2005HumanMS, title={Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion.}, author={Yasushi Sato and Hironobu Araki and Junji Kato and Kiminori Nakamura and Yutaka Kawano and Masayoshi Kobune and Tsutomu Sato and Koji Miyanishi and Tetsuji Takayama and Minoru Takahashi and Rishu Takimoto and Satoshi Iyama and Takuya Matsunaga and Seiji Ohtani and Akihiro Matsuura and H. A. Hamada and Yoshiro Niitsu}, journal={Blood}, year={2005}, volume={106 2}, pages={756-63} }