Human mesenchymal stem cells play a dual role on tumor cell growth in vitro and in vivo.

@article{Tian2011HumanMS,
  title={Human mesenchymal stem cells play a dual role on tumor cell growth in vitro and in vivo.},
  author={Lin Li Hui Tian and Weiming Yue and Feng Zhu and Shuhai Li and Wenjun Li},
  journal={Journal of cellular physiology},
  year={2011},
  volume={226 7},
  pages={1860-7}
}
Nowadays, some evidences demonstrate that human mesenchymal stem cells (hMSCs) favor tumor growth; however, others show that hMSCs can suppress tumorigenesis and tumor growth. With the indeterminateness of the effect of hMSCs on tumors, we investigated the effect of hMSCs on lung cancer cell line A549 and esophageal cancer cell line Eca-109 in vitro and in vivo. Our results revealed that hMSCs inhibited the proliferation and invasion of A549 and Eca-109 cells, arrested tumor cells in the G1… CONTINUE READING
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