Human mesenchymal stem cells in synovial fluid increase in the knee with degenerated cartilage and osteoarthritis

  title={Human mesenchymal stem cells in synovial fluid increase in the knee with degenerated cartilage and osteoarthritis},
  author={I. Sekiya and M. Ojima and S. Suzuki and M. Yamaga and M. Horie and H. Koga and K. Tsuji and K. Miyaguchi and S. Ogishima and Hiroshi Tanaka and T. Muneta},
  journal={Journal of Orthopaedic Research},
We investigated whether mesenchymal stem cells (MSCs) in synovial fluid (SF) increased in the knee with degenerated cartilage and osteoarthritis. SF was obtained from the knee joints of 22 patients with anterior cruciate ligament (ACL) injury during ACL reconstruction, and cartilage degeneration was evaluated arthroscopically. SF was also obtained from the knee joints of 6 healthy volunteers, 20 patients with mild osteoarthritis, and 26 patients with severe osteoarthritis, in which the grading… Expand
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  • 2020
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  • Biology, Medicine
  • Journal of orthopaedic research : official publication of the Orthopaedic Research Society
  • 2009
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