Human marginal zone B cells.

  title={Human marginal zone B cells.},
  author={J. C. Weill and Sandra Weller and C. Reynaud},
  journal={Annual review of immunology},
Human marginal zone (MZ) B cells are, in a sense, a new entity. Although they share many properties with their mouse counterpart, they also display striking differences, such as the capacity to recirculate and the presence of somatic mutations in their B cell receptor. These differences are the reason they are often not considered a separate, rodent-like B cell lineage, but rather are considered IgM memory B cells. We review here our present knowledge concerning this subset and the arguments in… CONTINUE READING

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