Human mannose-binding lectin inhibitor prevents myocardial injury and arterial thrombogenesis in a novel animal model.


Myocardial infarction and coagulation disorders are leading causes of disability and death in the world. An important role of the lectin complement pathway in myocardial infarction and coagulation has been demonstrated in mice genetically deficient in lectin complement pathway proteins. However, these studies are limited to comparisons between wild-type and… (More)
DOI: 10.1016/j.ajpath.2014.10.015