Human lysozyme as a potential diagnostic marker in malaria: a mechanistic study of haemozoin-induced monocyte degranulation

Abstract

Background Lysozymes are antibacterial proteins defined by their ability to hydrolyse beta-1,4-glycosidic linkage between N-acetylmuramic acid and N-acetylglucosamine of peptidoglycan in the cell wall of bacteria [1]. In the recent years, little evidence on their involvement in malaria pathogenesis has emerged. In Anopheles gambiae and stephensi, lysozyme… (More)
DOI: 10.1186/1475-2875-11-S1-P80

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