Human lymphoblastoid cell line panels: novel tools for assessing shared drug pathways.


AIMS While powerful in silico tools are emerging for predicting drug targets and pathways, general in vitro tools for assessing such predictions are lacking. We present a novel in vitro method for distinguishing shared versus distinct drug pathways based on comparative cell growth inhibition profiles across a small panel of human lymphoblastoid cell lines… (More)
DOI: 10.2217/pgs.10.27