Human lymphoblastoid B-cell lines reprogrammed to EBV-free induced pluripotent stem cells.

Abstract

Generation of patient-specific induced pluripotent cells (iPSCs) holds great promise for regenerative medicine. Epstein-Barr virus immortalized lymphoblastoid B-cell lines (LCLs) can be generated from a minimal amount of blood and are banked worldwide as cellular reference material for immunologic or genetic analysis of pedigreed study populations. We… (More)
DOI: 10.1182/blood-2011-01-332064

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