Human leukocyte antigen class I/II alleles and development of human papillomavirus-related cervical neoplasia: results from a case-control study conducted in the United States.

@article{Hildesheim1998HumanLA,
  title={Human leukocyte antigen class I/II alleles and development of human papillomavirus-related cervical neoplasia: results from a case-control study conducted in the United States.},
  author={Allan Hildesheim and Mark H. Schiffman and David R Scott and Darlene Marti and Teri L. Kissner and Mark E. Sherman and Andrew Glass and M. Michele Manos and Attila T Lorincz and Robert J. Kurman and Julie Buckland and Brenda B Rush and Mary N Carrington},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={1998},
  volume={7 11},
  pages={1035-41}
}
The host immune response to human papillomaviruses (HPVs) is believed to be an important determinant of progression of HPV-associated cervical neoplasia. Human leukocyte antigens (HLAs) are important in the presentation of foreign antigens to the immune system. Previous studies have suggested a possible association between HLA and cervical neoplasia, but the specific alleles found to be associated with disease have varied between studies. To further evaluate this issue, we conducted a nested… CONTINUE READING