Human leucocyte antigens in idiopathic nephrotic syndrome in children

  title={Human leucocyte antigens in idiopathic nephrotic syndrome in children},
  author={Hans Ruder and Karl Schaerer and Gerhard Opelz and Volker Lenhard and Ruediger Waldherr and D E M{\"u}ller-wiefel and A. -M. Wingen and J{\"u}rgen Dippell},
  journal={Pediatric Nephrology},
An association of the idiopathic nephrotic syndrome (NS) with certain human leucocyte antigens (HLA) has been reported repeatedly. The aim of this study is to characterize further the clinical and histological features of patients with NS in relation to their HLA phenotypes. HLA antigens were determined in 132 paediatric patients with NS. In 91 steroid-sensitive patients (usually associated with minimal glomerular changes), the antigen frequencies of HLA-DR3, HLA-DR7, and HLA-B8,-DR3 combined… CONTINUE READING