Human keratinocytes adhere to two distinct heparin-binding synthetic peptides derived from fibronectin.

@article{Wilke1991HumanKA,
  title={Human keratinocytes adhere to two distinct heparin-binding synthetic peptides derived from fibronectin.},
  author={Mark S Wilke and Amy P. N. Skubitz and Leo T. Furcht and James B. McCarthy},
  journal={The Journal of investigative dermatology},
  year={1991},
  volume={97 3},
  pages={573-9}
}
Fibronectin is present at the dermal-epidermal junction in normal skin and is increased in skin tissues in inflammatory diseases, skin cancers, and wound repair. The present studies focused on further characterizing the interaction between fibronectin and keratinocytes, specifically addressing whether human keratinocytes utilize multiple adhesion promoting sequences within fibronectin. Initially, direct cell-binding assays were utilized in which keratinocyte adhesion to plastic substrata coated… CONTINUE READING