Human kallikrein gene 5 (KLK5) expression is an indicator of poor prognosis in ovarian cancer

@article{Kim2001HumanKG,
  title={Human kallikrein gene 5 (KLK5) expression is an indicator of poor prognosis in ovarian cancer},
  author={Hyeja Kim and Andreas Scorilas and Dionyssios Katsaros and George M Yousef and Marco Massobrio and Stefano Fracchioli and Roberta Piccinno and G Gordini and Eleftherios P. Diamandis},
  journal={British Journal of Cancer},
  year={2001},
  volume={84},
  pages={643 - 650}
}
  • Hyeja Kim, Andreas Scorilas, +6 authors Eleftherios P. Diamandis
  • Published in British Journal of Cancer 2001
  • Medicine, Biology
  • Kallikrein gene 5 (KLK5, also known as KLK-L2), located on chromosome 19q13.4, is one of the newly identified members of the kallikrein gene family, which is a subgroup of the serine protease enzyme family. In normal human tissues, KLK5 is highly expressed in skin, mammary gland and testis. Preliminary RT-PCR analysis has indicated that KLK5 is expressed in a subset of ovarian tumours. We have thus hypothesized that KLK5 may be a new prognostic indicator in ovarian cancer. We have examined the… CONTINUE READING

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