Human intestinal B-cell blasts and plasma cells express the mucosal homing receptor integrin alpha 4 beta 7.

@article{Farstad1995HumanIB,
  title={Human intestinal B-cell blasts and plasma cells express the mucosal homing receptor integrin alpha 4 beta 7.},
  author={Inger Nina Farstad and Trond Sundby Halstensen and Andrew I. Lazarovits and Jarle Norstein and Olav Fausa and P E R Brandtzaeg},
  journal={Scandinavian journal of immunology},
  year={1995},
  volume={42 6},
  pages={662-72}
}
Interactions between homing receptors on circulating leucocytes and endothelial addressins regulate tissue-specific cellular extravasation. Although integrin alpha 4 beta 7 appears to be the main receptor for gut-homing T lymphocytes, less is known about molecules mediating mucosal B cell homing. Expression of integrin alpha 4 beta 7 on B lymphocytes, B cell blasts, and plasma cells in human gut-associated lymphoid tissue (GALT; the Peyer's patches and appendix) and lamina propria was studied… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 31 extracted citations

Similar Papers

Loading similar papers…