Human interstitial retinol-binding protein (IRBP): cloning, partial sequence, and chromosomal localization

@article{Liou1987HumanIR,
  title={Human interstitial retinol-binding protein (IRBP): cloning, partial sequence, and chromosomal localization},
  author={G. Liou and S. Fong and J. Gosden and P. Tuinen and D. Ledbetter and S. Christie and D. Rout and S. Bhattacharya and R. Cook and Y. Li and C. Wang and C. Bridges},
  journal={Somatic Cell and Molecular Genetics},
  year={1987},
  volume={13},
  pages={315-323}
}
  • G. Liou, S. Fong, +9 authors C. Bridges
  • Published 1987
  • Biology, Medicine
  • Somatic Cell and Molecular Genetics
  • A cloned 2184-bp cDNA coding for human interstitial retinol-binding protein (IRBP) has been isolated and sequenced. The probe hybridized to a 5.2-kb poly(A) RNA from human retinas. Nineteen tryptic peptides (363 amino acids) sequenced and purified from bovine IRBP could be aligned with 86–88% homology to the translated sequence. Two segments approximately 200 amino acids long were found to have a 41% residue identity,suggesting an internal duplication event. This cloned cDNA was used to probe… CONTINUE READING
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