Human interleukin-6 induces human herpesvirus-8 replication in a body cavity-based lymphoma cell line.

@article{Song2002HumanII,
  title={Human interleukin-6 induces human herpesvirus-8 replication in a body cavity-based lymphoma cell line.},
  author={Jian Song and Takako Ohkura and Masamichi Sugimoto and Yasuko Mori and Reiko Inagi and Koichi Yamanishi and Kazuyuki Yoshizaki and Norihiro Nishimoto},
  journal={Journal of medical virology},
  year={2002},
  volume={68 3},
  pages={404-11}
}
Human herpesvirus-8 (HHV-8) is etiologically associated with Kaposi's sarcoma (KS), body cavity-based lymphoma (BCBL), and multicentric Castleman's disease (MCD). These HHV-8-associated diseases arise predominantly in acquired immunodeficiency syndrome (AIDS) patients. Human interleukin-6 (huIL-6) elevated in the serum of AIDS patients is suggested to stimulate the growth of KS and BCBL and to augment the symptoms of MCD. To determine whether huIL-6 stimulates HHV-8 replication directly… CONTINUE READING

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