Human interactome resource and gene set linkage analysis for the functional interpretation of biologically meaningful gene sets

  title={Human interactome resource and gene set linkage analysis for the functional interpretation of biologically meaningful gene sets},
  author={Xiaoping Zhou and Pengcheng Chen and Qiang Wei and Xueling Shen and Xin Chen},
  volume={29 16},
MOTIVATION A molecular interaction network can be viewed as a network in which genes with related functions are connected. Therefore, at a systems level, connections between individual genes in a molecular interaction network can be used to infer the collective functional linkages between biologically meaningful gene sets. RESULTS We present the human interactome resource and the gene set linkage analysis (GSLA) tool for the functional interpretation of biologically meaningful gene sets… 

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