• Biology, Medicine
  • Published in Arthritis research & therapy 2008
  • DOI:10.1186/ar2448

Human infrapatellar fat pad-derived stem cells express the pericyte marker 3G5 and show enhanced chondrogenesis after expansion in fibroblast growth factor-2

@article{Khan2008HumanIF,
  title={Human infrapatellar fat pad-derived stem cells express the pericyte marker 3G5 and show enhanced chondrogenesis after expansion in fibroblast growth factor-2},
  author={Wasim S Khan and Simon R Tew and Adetola B Adesida and Tim E. Hardingham},
  journal={Arthritis Research & Therapy},
  year={2008},
  volume={10},
  pages={R74 - R74}
}
IntroductionInfrapatellar fat pad (IPFP) is a possible source of stem cells for the repair of articular cartilage defects. In this study, adherent proliferative cells were isolated from digests of IPFP tissue. The effects of the expansion of these cells in fibroblast growth factor-2 (FGF-2) were tested on their proliferation, characterisation, and chondrogenic potential.MethodsIPFP tissue was obtained from six patients undergoing total knee replacement, and sections were stained with 3G5, alpha… CONTINUE READING

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