Human in vitro 3D co-culture model to engineer vascularized bone-mimicking tissues combining computational tools and statistical experimental approach.

@article{Bersini2016HumanIV,
  title={Human in vitro 3D co-culture model to engineer vascularized bone-mimicking tissues combining computational tools and statistical experimental approach.},
  author={Simone Bersini and Mara Gilardi and C Arrigoni and Giuseppe Tal{\`o} and Moreno Zamai and Luigi Zagra and Valeria Caiolfa and Matteo Moretti},
  journal={Biomaterials},
  year={2016},
  volume={76},
  pages={
          157-72
        }
}
The generation of functional, vascularized tissues is a key challenge for both tissue engineering applications and the development of advanced in vitro models analyzing interactions among circulating cells, endothelium and organ-specific microenvironments. Since vascularization is a complex process guided by multiple synergic factors, it is critical to analyze the specific role that different experimental parameters play in the generation of physiological tissues. Our goals were to design a… CONTINUE READING
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