Human immunodeficiency viruses: SIV infection in wild gorillas

  title={Human immunodeficiency viruses: SIV infection in wild gorillas},
  author={Fran Van Heuverswyn and Yingying Li and Cécile Neel and Elizabeth Bailes and Brandon F. Keele and Weimin Liu and Severin Loul and Christelle Butel and Florian Li{\'e}geois and Yanga Bienvenue and Eitel Mpoudi Ngolle and Paul M. Sharp and George M. Shaw and Eric Delaporte and Beatrice H. Hahn and Martine Peeters},
Chimpanzees (Pan troglodytes troglodytes) from west central Africa are recognized as the reservoir of simian immunodeficiency viruses (SIVcpzPtt) that have crossed at least twice to humans: this resulted in the AIDS pandemic (from human immunodeficiency virus HIV-1 group M) in one instance and infection of just a few individuals in Cameroon (by HIV-1 group N) in another. A third HIV-1 lineage (group O) from west central Africa also falls within the SIVcpzPtt radiation, but the primate reservoir… 

Eastern Chimpanzees, but Not Bonobos, Represent a Simian Immunodeficiency Virus Reservoir

All newly identified SIVcpzPts strains clustered in strict accordance to their subspecies origin; however, they exhibited considerable genetic diversity, especially in protein domains known to be under strong host selection pressure, and cannot be explained by an insufficient primate reservoir.

A new human immunodeficiency virus derived from gorillas

A new human immunodeficiency virus is identified in a Cameroonian woman and shows no evidence of recombination with other HIV-1 lineages, and seems to be the prototype of a new HIV- 1 lineage that is distinct from HIV-2 groups M, N and O.

Simian retroviruses in African apes.

  • M. PeetersE. Delaporte
  • Biology
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
  • 2012
This work elaborate on how the recent development of non-invasive methods has allowed the reservoirs of the HIV-1 ancestors in chimpanzees and gorillas to be identified, and increased the knowledge of the natural history of SIV infections in chimpanzees.

Origin and Biology of Simian Immunodeficiency Virus in Wild-Living Western Gorillas

ABSTRACT Western lowland gorillas (Gorilla gorilla gorilla) are infected with a simian immunodeficiency virus (SIVgor) that is closely related to chimpanzee and human immunodeficiency viruses (SIVcpz

Into the wild: simian immunodeficiency virus (SIV) infection in natural hosts.

The Evolution of SIV in Primates and the Emergence of the Pathogen of AIDS

There are over 40 nonhuman primate species recognized to be infected with a species-specific simian immunodeficiency virus (SIV), all of them located in sub-Saharan Africa, and these include chimpanzees, western gorillas, and sooty mangabeys.

The origin and molecular epidemiology of HIV

The genetic diversity of HIV-1 continues to increase overtime due to demographic factors such as travel and migration and frequent co/superinfections, which leads to an increasing number of drug-resistant strains, especially in resource limited countries.

Isolation of a simian immunodeficiency virus from a malbrouck (Chlorocebus cynosuros)

The first described SIV (SIVagmMAL-ZMB) from a malbrouck (Chlorocebus cynosuros) is reported, which possessed <80% nucleotide sequence identity to known SIV isolates and was located basally to vervet monkey SIV strains in all phylogenies.



Chimpanzee Reservoirs of Pandemic and Nonpandemic HIV-1

By sequence analysis of endemic SIVcpz strains, this work could trace the origins of pandemic and nonpandemic HIV-1 to distinct, geographically isolated chimpanzee communities and establish P. t.

Simian Immunodeficiency Virus Infection of Chimpanzees

Simian immunodeficiency viruses are primate lentiviruses that infect no fewer than 36 different nonhuman primate species in sub-Saharan Africa and two of these viruses, SIVcpz from chimpanzees and SIVsmm from sooty mangabeys, have been identified.

New Simian Immunodeficiency Virus Infecting De Brazza's Monkeys (Cercopithecus neglectus): Evidence for a Cercopithecus Monkey Virus Clade

The molecular characterization of a lentivirus (SIVdeb) naturally infecting De Brazza's monkeys and the consistent clustering of SIVdeb with SIVsyk and the SIVmon/Sivmus/SIVgsn group suggests that these viruses have evolved from a common ancestor that likely infected a Cercopithecus host in the distant past.

Survey of gorillas (Gorilla gorilla gorilla) and chimpanzees (Pan troglodytes troglodytes) in Southwestern Cameroon

In unlogged forest, old secondary forests and areas of recent logging with large remaining patches of primary forest, significantly higher densities were calculated than inside the more heavily exploited logging concession.

Behavioral Ecology of Sympatric Chimpanzees and Gorillas in Bwindi Impenetrable National Park, Uganda: Diet

It is found that chimpanzee and gorilla diets are seasonally similar, but diverge during lean seasons, and three factors—seasonal consumption of fibrous foods by gorillas, interspecific differences in preferred fruit species, and meat consumption by chimpanzees—contributed to dietary divergence.