Human immunodeficiency virus type 1 Vpr: functions and molecular interactions.

@article{Romani2009HumanIV,
  title={Human immunodeficiency virus type 1 Vpr: functions and molecular interactions.},
  author={Bizhan Romani and Susan Engelbrecht},
  journal={The Journal of general virology},
  year={2009},
  volume={90 Pt 8},
  pages={1795-805}
}
Human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) is an accessory protein that interacts with a number of cellular and viral proteins. The functions of many of these interactions in the pathogenesis of HIV-1 have been identified. Deletion of the vpr gene reduces the virulence of HIV-1 dramatically, indicating the importance of this protein for the virus. This review describes the current findings on several established functions of HIV-1 Vpr and some possible roles proposed for… CONTINUE READING

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  • Yedavalli, K V.S.R., +8 authors L. M. Huang
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