Human immunodeficiency virus type 1 Rev-responsive element RNA binds to host cell-specific proteins.

@article{Shukla1994HumanIV,
  title={Human immunodeficiency virus type 1 Rev-responsive element RNA binds to host cell-specific proteins.},
  author={Ram R Shukla and Paul L. Kimmel and Anvita Kumar},
  journal={Journal of virology},
  year={1994},
  volume={68 4},
  pages={2224-9}
}
RNase protection-gel retention studies show human host cell-specific ribonucleoprotein complexes with human immunodeficiency virus type 1 Rev-responsive element (RRE) RNA. Nuclear proteins from rodent or murine cells appear to lack the ability to form these complexes. Human-mouse somatic cell hybrids retaining a single human chromosome, either 6 or 12, form the RRE-nuclear-protein complexes. One of the complexes requires the entire RRE RNA, while the other needs RRE RNA stem-loops 1 and 2 only… CONTINUE READING