Human immunodeficiency virus infection as risk factor for mother-to-child hepatitis C virus transmission; persistence of anti-hepatitis C virus in children is associated with the mother's anti-hepatitis C virus immunoblotting pattern.

@article{Manzini1995HumanIV,
  title={Human immunodeficiency virus infection as risk factor for mother-to-child hepatitis C virus transmission; persistence of anti-hepatitis C virus in children is associated with the mother's anti-hepatitis C virus immunoblotting pattern.},
  author={Paola Manzini and Giorgio Saracco and A Cerchier and Chiara Riva and Alfredo Musso and Emanuela Ricotti and Elvia Palomba and Carlo Scolfaro and Giorgio Verme and Ferruccio Bonino},
  journal={Hepatology},
  year={1995},
  volume={21 2},
  pages={328-32}
}
To determine the rate of vertical transmission of hepatitis C virus (HCV), we prospectively studied 45 babies born to anti-HCV-positive women with or without concomitant infection with the human immunodeficiency virus (HIV). We performed a second-generation recombinant immunoblotting assay, alanine transaminase (ALT) evaluation, and HCV-RNA testing on sera from 27 infants of HCV+, HIV- mothers and 18 babies of HCV+, HIV+ women, at birth and thereafter. After birth, HCV antibodies progressively… CONTINUE READING
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