Human immunodeficiency virus and the central nervous system.

@article{Spencer1992HumanIV,
  title={Human immunodeficiency virus and the central nervous system.},
  author={Dorothy Spencer and Richard W. Price},
  journal={Annual review of microbiology},
  year={1992},
  volume={46},
  pages={655-93}
}
Neurological disease frequently complicates HIV-1 infection. In addition to opportunistic infections, a syndrome of combined cognitive and motor impairment, referred to as the AIDS dementia complex, has been recognized. While presumed to relate to HIV-1 itself, the pathogenesis of this syndrome remains uncertain. Because of the limited extent of productive brain HIV-1 infection in many cases, and because such infection involves macrophages and microglia rather than cells of neuroectodermal… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 40 extracted citations

HIV Neuropathogenesis: a Tight Rope Walk of Innate Immunity

Journal of Neuroimmune Pharmacology • 2010
View 10 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…