Human immunodeficiency virus (HIV) leukoencephalopathy and the microcirculation.

  title={Human immunodeficiency virus (HIV) leukoencephalopathy and the microcirculation.},
  author={Thomas R. Smith and Umberto Degirolami and Dominique H{\'e}nin and Francis Bolgert and J. J. Hauw},
  journal={Journal of neuropathology and experimental neurology},
  volume={49 4},
We studied the brains of three patients with acquired immune deficiency syndrome (AIDS), all of whom developed subacutely progressive dementia unassociated with opportunistic infection or neoplasm in the central nervous system. Computed tomographic (CT) scans of the head revealed cortical atrophy, ventricular dilation, and diffuse hypodensity of the centrum semiovale. On microscopic examination, the cerebral and cerebellar white matter in all cases showed diffuse and focal, angiocentric regions… CONTINUE READING


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