Human immunodeficiency virus: Phylogeny and the origin of HIV-1

  title={Human immunodeficiency virus: Phylogeny and the origin of HIV-1},
  author={Andrew Rambaut and David L. Robertson and Oliver G. Pybus and Martine Peeters and Edward C. Holmes},
The origin of human immunodeficiency virus type 1 (HIV-1) is controversial. We show here that viruses obtained from the Democratic Republic of Congo in Africa have a quantitatively different phylogenetic tree structure from those sampled in other parts of the world. This indicates that the structure of HIV-1 phylogenies is the result of epidemiological processes acting within human populations alone, and is not due to multiple cross-species transmission initiated by oral polio vaccination. 
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