Human iPSC-MSC-Derived Xenografts Modulate Immune Responses by Inhibiting the Cleavage of Caspases.

@article{Li2017HumanIX,
  title={Human iPSC-MSC-Derived Xenografts Modulate Immune Responses by Inhibiting the Cleavage of Caspases.},
  author={Cheng-Lin Li and Yun Leng and Bin Zhao and Chang Gao and Fei-Fei Du and Ning Jin and Qi-zhou Lian and Shuang-Yue Xu and Guo-liang Yan and Jun-jie Xia and Guo-hong Zhuang and Qing-Ling Fu and Zhongquan Qi},
  journal={Stem cells},
  year={2017},
  volume={35 7},
  pages={1719-1732}
}
Mesenchymal stem cells (MSCs) negatively modulate immune properties. Induced pluripotent stem cells (iPSCs)-derived MSCs are alternative source of MSCs. However, the effects of iPSC-MSCs on T cells phenotypes in vivo remain unclear. We established an iPSC-MSC-transplanted host versus graft reaction mouse model using subcapsular kidney injection. Th1, Th2… CONTINUE READING