Human hypocretin and melanin concentrating hormone levels are linked to emotion and social interaction

@article{Blouin2013HumanHA,
  title={Human hypocretin and melanin concentrating hormone levels are linked to emotion and social interaction},
  author={A. Blouin and I. Fried and Charles L. Wilson and R. Staba and E. Behnke and H. Lam and N. Maidment and K. Karlsson and J. Lapierre and J. Siegel},
  journal={Nature communications},
  year={2013},
  volume={4},
  pages={1547 - 1547}
}
The neurochemical changes underlying human emotions and social behavior are largely unknown. Here we report on the changes in the levels of two hypothalamic neuropeptides, hypocretin-1 (Hcrt-1) and melanin concentrating hormone (MCH), measured in the human amygdala. We show that Hcrt-1 levels are maximal during positive emotion, social interaction, and anger, behaviors that induce cataplexy in human narcoleptics. In contrast, MCH levels are minimal during social interaction, but are increased… Expand
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