Human hypertrophic scar-like nude mouse model: characterization of the molecular and cellular biology of the scar process.

@article{Wang2011HumanHS,
  title={Human hypertrophic scar-like nude mouse model: characterization of the molecular and cellular biology of the scar process.},
  author={Jianfei Wang and Jie Ding and Haiyan Jiao and Dariush Honardoust and Moein Momtazi and Heather A. Shankowsky and Edward E. Tredget},
  journal={Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society},
  year={2011},
  volume={19 2},
  pages={274-85}
}
Hypertrophic scar (HTS) following thermal injury and other forms of trauma is a dermal fibroproliferative disorder that leads to considerable morbidity. Because of the lack of an ideal animal model, research is difficult. We have established an HTS model that involves transplanting human split-thickness skin graft (STSG) or full-thickness skin graft (FTSG… CONTINUE READING