Human herpesviruses-6, -7 and -8 in organ transplant recipients.

  • Nina Singh
  • Published 2000 in
    Clinical microbiology and infection : the…

Abstract

The newer herpesviruses are being increasingly recognized as significant opportunistic pathogens in organ transplant recipients. Published data support the role of human herpesvirus-6 as a potential cause of encephalitis and bone marrow suppression in transplant setting. An association of human herpesvirus-6 with fungal infections and cytomegalovirus infection has also been documented. Human herpesvirus-7 also appears to be an immunomodulatory agent and may facilitate the pathogenicity of cytomegalovirus. Unlike human herpesviruses -6 and -7, human herpesvirus -8 is not ubiquitous; its seroprevalence exhibits wide geographic variation. Human herpesvirus-8 has been causally associated with post-transplant Kaposi's sarcoma. The complete spectrum of pathogenicity and ultimately the effective prophylaxis and management of these viruses has yet to be fully elucidated.

050100'02'04'06'08'10'12'14'16
Citations per Year

241 Citations

Semantic Scholar estimates that this publication has 241 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Singh2000HumanH, title={Human herpesviruses-6, -7 and -8 in organ transplant recipients.}, author={Nina Singh}, journal={Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases}, year={2000}, volume={6 9}, pages={453-9} }