Human herpesvirus 6A DNA Is detected frequently in plasma but rarely in peripheral blood leukocytes of patients after bone marrow transplantation.

@article{Nitsche2001HumanH6,
  title={Human herpesvirus 6A DNA Is detected frequently in plasma but rarely in peripheral blood leukocytes of patients after bone marrow transplantation.},
  author={Andreas Nitsche and Christoph W M{\"u}ller and Aleksandar Radonic and Olfert Landt and Heinz Ellerbrok and Georg Pauli and Wolfgang Siegert},
  journal={The Journal of infectious diseases},
  year={2001},
  volume={183 1},
  pages={130-3}
}
A real-time quantitative polymerase chain reaction assay was devised to determine the load of human herpesvirus (HHV)-6A and -6B DNA in paired samples of plasma and peripheral blood leukocytes (PBL) of 25 bone marrow transplant patients. The assay detects HHV-6 DNA variants A and B in a linear range of 10(7)-10(1) genome equivalents per assay. Viral DNA was measured in 336 paired DNA PBL samples and in corresponding plasma samples. HHV-6A and/or -6B DNA was detected in PBL of 23 of 25 patients… CONTINUE READING

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