Human herpesvirus 1 UL24 gene encodes a potential PD-(D/E)XK endonuclease.

@article{Knizewski2006HumanH1,
  title={Human herpesvirus 1 UL24 gene encodes a potential PD-(D/E)XK endonuclease.},
  author={Lukasz Knizewski and Lisa N. Kinch and Nick V. Grishin and Leszek Rychlewski and Krzysztof Ginalski},
  journal={Journal of virology},
  year={2006},
  volume={80 5},
  pages={2575-7}
}
Using Meta-BASIC, a highly sensitive method for detection of distant similarity between proteins, we have identified another potential PD-(D/E)XK endonuclease in human herpesvirus 1 (HHV-1) encoded by the UL24 gene. The universal presence of UL24 in completed herpesviral genomes of three major subfamilies, Alphaherpesvirinae, Betaherpesvirinae, and Gammaherpesvirinae, suggests a fundamental role for this predicted PD-(D/E)XK endonuclease activity in the viral life cycle. 

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