Human heart-type cytoplasmic fatty acid-binding protein (H-FABP) for the diagnosis of acute myocardial infarction. Clinical evaluation of H-FABP in comparison with myoglobin and creatine kinase isoenzyme MB.

@article{Okamoto2000HumanHC,
  title={Human heart-type cytoplasmic fatty acid-binding protein (H-FABP) for the diagnosis of acute myocardial infarction. Clinical evaluation of H-FABP in comparison with myoglobin and creatine kinase isoenzyme MB.},
  author={Fumio Okamoto and Ko-ichi Sohmiya and Yasuhiko Ohkaru and Ken-ichi Kawamura and Kumiko Asayama and Hiroshi Kimura and Satoshi Nishimura and Hiroaki Ishii and Nanae Sunahara and Takao Tanaka},
  journal={Clinical chemistry and laboratory medicine},
  year={2000},
  volume={38 3},
  pages={231-8}
}
Heart-type fatty acid-binding protein (H-FABP) is a low molecular weight cytoplasmic protein and present abundantly in the myocardium. When the myocardium is injured, as in the case of myocardial infarction, low molecular weight cytoplasmic proteins including H-FABP are released into the circulation and H-FABP is detectable in a blood sample. We have already developed a direct sandwich-ELISA for quantification of human H-FABP using two distinct types of monoclonal antibodies specific for human… CONTINUE READING
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