Human hair growth deficiency is linked to a genetic defect in the phospholipase gene LIPH.

@article{Kazantseva2006HumanHG,
  title={Human hair growth deficiency is linked to a genetic defect in the phospholipase gene LIPH.},
  author={Anastasiya Kazantseva and Andrey Y Goltsov and Rena A Zinchenko and Anastasia P. Grigorenko and Anna V Abrukova and Yuri K. Moliaka and Alexander G Kirillov and Zhiru Guo and Stephen Lyle and Evgeny K Ginter and Evgeny I. Rogaev},
  journal={Science},
  year={2006},
  volume={314 5801},
  pages={982-5}
}
The molecular mechanisms controlling human hair growth and scalp hair loss are poorly understood. By screening about 350,000 individuals in two populations from the Volga-Ural region of Russia, we identified a gene mutation in families who show an inherited form of hair loss and a hair growth defect. Affected individuals were homozygous for a deletion in the LIPH gene on chromosome 3q27, caused by short interspersed nuclear element-retrotransposon-mediated recombination. The LIPH gene is… CONTINUE READING
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