Human hair greying is linked to a specific depletion of hair follicle melanocytes affecting both the bulb and the outer root sheath.

@article{Commo2004HumanHG,
  title={Human hair greying is linked to a specific depletion of hair follicle melanocytes affecting both the bulb and the outer root sheath.},
  author={St{\'e}phane F Commo and Olivier Gaillard and Bruno A Bernard},
  journal={The British journal of dermatology},
  year={2004},
  volume={150 3},
  pages={435-43}
}
BACKGROUND Although hair greying is a very common phenomenon characterized by loss of pigment in the hair shaft, the events that cause and control natural hair whitening with age in humans are still unclear. OBJECTIVES To decipher the origin of natural hair whitening. METHODS Human hair melanocytes were immunohistochemically characterized at different stages of whitening. RESULTS Loss of hair shaft melanin was found to be associated with a decrease in both bulb melanin content and bulb… CONTINUE READING
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