Human granulocyte/pollen-binding protein. Recognition and identification as transferrin.

  title={Human granulocyte/pollen-binding protein. Recognition and identification as transferrin.},
  author={S P Sass-Kuhn and Redwan Moqbel and J Andrew MacKay and O. Cromwell and Antony B. Kay},
  journal={The Journal of clinical investigation},
  volume={73 1},
Normal human serum was found to contain a heat-stable protein which promoted the binding of granulocytes to timothy grass pollen (granulocyte/pollen-binding protein [GPBP]). GPBP was purified by gel filtration, anion exchange, and affinity chromatography. Virtually all of the granulocyte/pollen-binding activity was associated with a beta-1-protein having a molecular mass of approximately 77,000 D and an isoelectric point of between 5.5 and 6.1. By immunoelectrophoresis and sodium dodecyl… CONTINUE READING


Publications referenced by this paper.
Showing 1-10 of 10 references

Identification of the binding site for transferrin in human reticulocytes

  • D. R. Sutherland, D. Delia, C. Schneider, R. A. Newman, J. Kemshead, M. F. Greaves
  • Biochem . Biophys . Res . Commun .
  • 1981

Structure and function of transferrin

  • M Steiner
  • Prog . Hematol .
  • 1980

Transferrin in normal cerebrospinal fluid

  • E. H. Morgan
  • Nature ( Lond . ) .
  • 1974

Studies on the transferrins of adult serum , cord serum , and cerebrospinal fluid . The effect of neuraminidase

  • J. Fletcher
  • J . Exp . Med .
  • 1968

Transferrin and transferrin iron

  • W. C. Parker
  • 1962

Chemical composition of human tracheo - bronchial secretions

  • J. Clausen, T. Munkner
  • 1961

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