Human glutathione S-transferases: radioimmunoassay studies on the expression of alpha-, mu- and pi-class isoenzymes in developing lung and kidney.

@article{Beckett1990HumanGS,
  title={Human glutathione S-transferases: radioimmunoassay studies on the expression of alpha-, mu- and pi-class isoenzymes in developing lung and kidney.},
  author={Geoff J. Beckett and Alexander F Howie and Robert Hume and B Matharoo and Charlotte Hiley and Pamala Jones and Richard C. Strange},
  journal={Biochimica et biophysica acta},
  year={1990},
  volume={1036 3},
  pages={176-82}
}
The developmental expression of the alpha-, mu- and pi-class glutathione S-transferases has been defined in human lung and kidney using radioimmunoassay, immunohistochemistry and column chromatography. Expression of alpha-class enzymes increased significantly after about 40 weeks gestation in kidney but not lung, while expression of mu isoenzymes was continuous throughout development in both tissues. Expression of the pi isoenzyme fell during in utero ontogeny in lung, the pattern of down… CONTINUE READING