Human glioma-associated antigens detected by monoclonal antibodies.

@article{Schnegg1981HumanGA,
  title={Human glioma-associated antigens detected by monoclonal antibodies.},
  author={J. F. Schnegg and A. C. Diserens and Stefan Carrel and Roberto S Accolla and Nicolas de Tribolet},
  journal={Cancer research},
  year={1981},
  volume={41 3},
  pages={
          1209-13
        }
}
Hybridoma cells were derived from a fusion between mouse P3x63/Ag8 myeloma cells and spleen cells from a mouse immunized with whole cells of a human malignant glioma line. Of 345 hybrids obtained, 36 secreted antibodies that reacted with the glioma cell line used for immunization as assayed by an indirect antibody-binding radioimmunoassay. After a first screening for the absence of reactivity on two nongliogenous cell lines, 3 hybrids were selected and cloned by limiting dilution. The… CONTINUE READING

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 36 CITATIONS

Oncology of the Nervous System

Michael D. Walker
  • Cancer Treatment and Research
  • 1983
VIEW 6 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Monoclonal antibodies reveal multiple forms of expression of human microsomal epoxide hydrolase.

  • Toxicology and applied pharmacology
  • 2012
VIEW 3 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Clinical Evaluation of Antitumor Therapy

Franco M. Muggia, Marcel Rozencweig
  • Developments in Oncology
  • 1987
VIEW 5 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED